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Oxidative Stress Neurons

Meaning

Oxidative Stress Neurons describes the pathological state where nerve cells are subjected to an overwhelming accumulation of reactive oxygen species (ROS) and reactive nitrogen species (RNS), exceeding the neuron’s endogenous antioxidant capacity. This imbalance leads to molecular damage to DNA, lipids, and proteins, significantly impairing neuronal function and contributing to neuroinflammation and accelerated cell death. This condition is a primary mechanistic driver in the pathogenesis of numerous neurodegenerative disorders.