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Oxidative Stress Mitigation

Meaning

Oxidative stress mitigation is the physiological and therapeutic strategy aimed at reducing the cellular damage caused by an imbalance between the production of reactive oxygen species (ROS) and the cell’s capacity to detoxify these reactive intermediates. Excessive oxidative stress damages lipids, proteins, and DNA, accelerating cellular senescence and contributing to the pathology of numerous chronic diseases. Mitigation efforts focus on bolstering endogenous antioxidant defenses and reducing ROS generation.