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Överkalix Study

Meaning

The Överkalix Study is a landmark epidemiological investigation that explored the impact of nutritional availability, specifically during the slow growth periods of pre-puberty, on the long-term health and mortality of subsequent generations. This unique, multigenerational study focused on a geographically isolated population in Northern Sweden, meticulously utilizing historical harvest records to correlate grand-parental food supply with descendant health outcomes. It provided early, compelling evidence for the concept of transgenerational epigenetic inheritance in humans.