What is the Origin of Ovarian Reserve Management?

The term is central to modern fertility medicine, emerging from the development of sensitive biomarkers like Anti-Müllerian Hormone (AMH) and antral follicle count (AFC) for quantitative assessment. The "Management" aspect signifies a proactive, therapeutic approach to an otherwise irreversible biological decline, integrating research from gerontology and reproductive biology.

What is the Mechanism of Ovarian Reserve Management?

Management strategies often focus on improving the microenvironment of the ovarian follicles, reducing oxidative stress, and enhancing mitochondrial function within the oocytes. While the total number of primordial follicles is finite, interventions may include targeted nutraceuticals, lifestyle adjustments, and potentially specific peptide or hormonal therapies designed to modulate gonadotropin signaling and improve local ovarian blood flow.

Ovarian Reserve Management

Meaning

Ovarian Reserve Management is the clinical practice of assessing, monitoring, and implementing strategies to preserve or optimize the quantity and quality of a woman’s remaining oocytes. This is a critical aspect of reproductive endocrinology, particularly relevant for fertility planning and understanding the timeline of reproductive aging. Management protocols aim to slow the rate of follicle depletion and improve oocyte viability.