What is the Origin of Ovarian Reserve AMH?

AMH originates from the Müllerian inhibiting substance produced by fetal Sertoli cells, which causes regression of female internal reproductive ducts; in adult females, it is produced by granulosa cells of preantral and small antral follicles. The term 'Ovarian Reserve' is clinical jargon describing the finite number of eggs remaining. The combination provides a contemporary, measurable proxy for follicular endowment.

What is the Mechanism of Ovarian Reserve AMH?

AMH functions locally within the ovary by inhibiting the recruitment of primordial follicles into the growing pool, thereby conserving the reserve for future cycles. Systemically, its concentration in the peripheral blood correlates inversely with the total number of small follicles present, as these cells are its main source. Therefore, the mechanism of action as a marker is directly tied to the population dynamics of the early-stage follicular cohort.

Ovarian Reserve AMH ∞ Area

Ovarian Reserve AMH

Meaning

Ovarian Reserve AMH refers to the quantitative assessment of a woman’s remaining pool of primordial follicles, using the measurement of Anti-Müllerian Hormone (AMH) as the primary surrogate biochemical marker. A robust reserve indicates a higher potential for viable oocyte yield in fertility treatments, while diminished levels suggest approaching ovarian senescence. This assay is invaluable in reproductive endocrinology planning.