Ovarian Function Support encompasses clinical and lifestyle strategies aimed at optimizing the endocrine and reproductive health of the ovaries throughout a woman’s lifespan, particularly focusing on maintaining follicular reserve and steroid hormone production. This support is crucial for regulating the menstrual cycle, preserving fertility, and ensuring adequate levels of estrogen and progesterone, which impact bone density, cardiovascular health, and neurocognitive function.
Origin
This term is rooted in reproductive endocrinology, drawing from the understanding of the hypothalamic-pituitary-ovarian (HPO) axis. The concept of “Support” emphasizes proactive intervention to counteract age-related decline, which begins well before menopause. Clinical interest has grown due to the recognition of ovarian hormones as systemic regulators of female health and longevity.
Mechanism
Effective support targets the regulation of gonadotropin signaling, specifically Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH), which govern follicular development and ovulation. Furthermore, it involves protecting the ovarian follicles from oxidative stress and mitochondrial dysfunction, key drivers of oocyte aging. Maintaining a healthy balance of estrogen and progesterone ensures proper feedback loops within the HPO axis and sustained systemic endocrine benefits.
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