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Osteoblastogenesis

Meaning

Osteoblastogenesis is the specialized biological process of progenitor cell differentiation into mature osteoblasts, the cells responsible for synthesizing new bone matrix and regulating bone mineralization. This process is absolutely critical for skeletal development, continuous bone remodeling, and the repair of microfractures throughout life. Optimal osteoblastogenesis is directly regulated by a precise interplay of systemic hormones and local growth factors, serving as a key metric for bone health and fracture risk.