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Ospemifene

Meaning

Ospemifene is an oral, non-steroidal drug classified as a Selective Estrogen Receptor Modulator (SERM), clinically approved for the treatment of moderate to severe dyspareunia, or painful intercourse, a common symptom of vulvar and vaginal atrophy associated with menopause. This medication selectively acts as an estrogen agonist in the vaginal epithelium, promoting tissue maturation and lubrication, while exhibiting anti-estrogenic or neutral effects in other tissues like the breast and endometrium. It represents a targeted therapeutic option for improving the quality of life for women experiencing genitourinary symptoms of menopause.