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Orthotopic Transplantation

Meaning

Orthotopic Transplantation is a surgical procedure where a graft of tissue or an entire organ is transplanted into the recipient at its natural, anatomically correct site. In the specialized context of fertility preservation, this refers specifically to the reimplantation of cryopreserved ovarian tissue back into the pelvic cavity, often onto the remaining ovarian remnant or the peritoneal surface. This precise anatomical placement is essential for ensuring the graft can re-establish its neurovascular connections and resume endocrine function in the most physiological manner possible.