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Orexin-A

Meaning

Orexin-A, also known as hypocretin-1, is a crucial neuropeptide hormone produced primarily by neurons in the lateral hypothalamus, playing a vital role in regulating wakefulness, appetite, and energy expenditure. This potent molecule acts as a stability factor for the wake state, preventing transitions into sleep and contributing to vigilance and cognitive function throughout the day. Its proper function is integral to maintaining the circadian rhythm and overall metabolic homeostasis.