What is the Origin of Orexigenic Hormone?

The term is a combination of the Greek orexis, meaning appetite or desire, and 'genic,' meaning producing. Its clinical recognition is tied to the discovery of the central nervous system's sophisticated control over energy intake.

What is the Mechanism of Orexigenic Hormone?

The quintessential orexigenic hormone is ghrelin, which is released from the gastric mucosa, especially during periods of fasting or caloric restriction. Ghrelin crosses the blood-brain barrier to bind to receptors in the hypothalamus, particularly the arcuate nucleus, where it stimulates the synthesis and release of potent neuropeptides that drive the powerful sensation of hunger. This mechanism ensures the organism seeks nourishment when energy reserves are low.

Orexigenic Hormone ∞ Area

Orexigenic Hormone

Meaning

An Orexigenic Hormone is a signaling molecule secreted by the endocrine system that primarily acts to stimulate appetite and increase food intake. These hormones are essential components of the homeostatic mechanism that regulates energy balance and body weight. Dysregulation of these potent signals contributes significantly to disorders of appetite and weight management.