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Oral Peptide Administration

Meaning

Oral Peptide Administration refers to the therapeutic delivery method where biologically active peptide-based compounds are formulated for ingestion by mouth, with the clinical goal of achieving systemic absorption and subsequent biological activity. This non-invasive route is highly preferred for enhancing patient compliance but presents substantial pharmacological challenges due to the peptide’s inherent susceptibility to enzymatic degradation within the gastrointestinal tract. Clinical development in this domain focuses on innovative formulations to successfully overcome the formidable biological barriers of the digestive system.