Optimized Neurogenesis describes the state where the rate of production and integration of new, functional neurons, particularly in neurogenic zones like the hippocampus, is actively promoted beyond baseline levels through targeted interventions. This process is essential for mood regulation and cognitive reserve. We are actively encouraging brain cell birth.
Origin
Stemming from developmental neuroscience, neurogenesis is the natural formation of neurons; optimization implies applying specific clinical levers to increase this inherent rate. This moves the process from passive occurrence to active enhancement.
Mechanism
This optimization is often facilitated by systemic factors, including appropriate sex hormone support and a significant reduction in chronic glucocorticoid exposure, which are known inhibitors of progenitor cell proliferation. Elevated levels of growth factors like BDNF directly signal for increased neuronal proliferation and survival.
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