A strategic health objective focused on maximizing the period of high-quality health (healthspan) and functional independence, while simultaneously minimizing the duration of morbidity and age-related disease at the very end of life. This compression does not necessarily extend maximum lifespan but ensures that almost the entire life is lived in a state of high vitality. It is the ultimate goal of preventative and longevity medicine.
Origin
This term is a refined concept within gerontology and public health, moving the focus from simply extending life (lifespan) to improving the quality of life lived (healthspan). The underlying principle is the delay of chronic disease onset.
Mechanism
The strategy operates by systematically addressing the fundamental hallmarks of aging, including cellular senescence, chronic inflammation, and endocrine decline, throughout the adult lifespan. By maintaining youthful hormonal balance, supporting telomere length, and enhancing cellular repair mechanisms, the onset of age-related physiological breakdown is significantly postponed, effectively compressing the period of sickness into a much shorter time frame.
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