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Optimized Energy Substrate Utilization

Meaning

The physiological state characterized by the highly efficient, flexible, and timely use of various metabolic fuels—primarily glucose, fatty acids, and ketones—to meet the energy demands of all body tissues, including the brain and muscle. Optimization implies a high degree of metabolic flexibility, allowing the body to seamlessly switch between energy sources based on availability and need. This is a critical indicator of overall metabolic health and a key objective in nutritional and hormonal wellness strategies. Efficient utilization minimizes energy waste and prevents accumulation of harmful metabolic byproducts.