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Optimized Energy Substrate

Meaning

Optimized Energy Substrate refers to the clinical goal of ensuring that the body’s primary fuel sources—predominantly glucose and fatty acids—are efficiently metabolized and readily available to all tissues, particularly the brain and muscle. This state is characterized by high mitochondrial efficiency, stable blood glucose control, and metabolic flexibility, allowing the body to seamlessly switch between different fuel sources based on demand. Achieving this optimization is essential for sustained physical and mental energy.