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Optimized Circadian Output

Meaning

The clinical state where the body’s intrinsic 24-hour biological clock, governed by the suprachiasmatic nucleus (SCN) and peripheral oscillators, is precisely synchronized with the external light-dark cycle and behavioral rhythms. This optimization ensures the timely and appropriate pulsatile release of key hormones, such as cortisol and melatonin, and the proper cycling of metabolic processes. Achieving an optimized circadian output is essential for restorative sleep, metabolic efficiency, and robust endocrine function, profoundly impacting overall health and mood.