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Operational Biological Baseline

Meaning

The Operational Biological Baseline represents the established, stable physiological and biochemical state of an individual, defined by a comprehensive set of measurable biomarkers that reflect optimal health and functional capacity. This baseline serves as the personal reference point against which all subsequent physiological changes, interventions, and disease progression are measured. Establishing this precise baseline is a critical first step in personalized medicine, providing objective data on hormonal levels, metabolic flexibility, inflammatory markers, and cellular health. Deviations from this optimal baseline indicate a decline in systemic function and signal the need for targeted clinical intervention.