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Obesity and Fertility

Meaning

The relationship between Obesity and Fertility describes the clinically significant bidirectional influence where excessive adipose tissue, particularly visceral fat, negatively impacts reproductive function in both males and females. Obesity is recognized as a state of chronic low-grade inflammation and metabolic dysregulation that profoundly disrupts the delicate balance of the hypothalamic-pituitary-gonadal (HPG) axis. This disruption often leads to conditions like anovulation, polycystic ovary syndrome (PCOS) in women, and reduced sperm quality in men. Addressing metabolic health is therefore a critical component of any comprehensive fertility intervention.