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Nutrient Sensing Network

Meaning

The Nutrient Sensing Network encompasses the integrated cellular and molecular pathways that monitor the body’s internal energy status, including availability of macronutrients like glucose, fatty acids, and amino acids. This network governs the switch between anabolic (building) and catabolic (breaking down) states based on real-time resource assessment. Key components include the mTOR, AMPK, and sirtuin signaling systems. Clarity within this network is essential for metabolic adaptation and hormonal signaling fidelity. Dysregulation directly impacts energy homeostasis.