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Nose-to-Brain Pathway

Meaning

The Nose-to-Brain Pathway, also known as the olfactory or intranasal route, describes a non-invasive route of drug administration that allows therapeutic agents, including certain hormones and peptides, to bypass the blood-brain barrier and directly enter the central nervous system. This anatomical connection leverages the olfactory and trigeminal nerves, providing a potential avenue for targeted delivery to the brain and cerebrospinal fluid. This delivery system holds significant promise for neurological and neuroendocrine treatments.