Skip to main content

Non-Senescent Physiology

Meaning

Non-Senescent Physiology describes a state of cellular and systemic health characterized by the minimal presence of senescent cells, which are metabolically active but non-dividing cells that accumulate with age and secrete pro-inflammatory factors. Achieving this state implies a high degree of cellular resilience, efficient tissue repair, and a low level of chronic, sterile inflammation, often termed inflammaging. This is a central goal of longevity medicine, aiming to preserve youthful tissue function and extend healthspan by mitigating the detrimental effects of cellular aging.