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Non-Senescent Cognition

Meaning

Non-Senescent Cognition describes a state of brain function characterized by preserved or enhanced cognitive abilities that resist the typical age-related decline associated with cellular senescence and neuroinflammation. This includes maintaining high levels of executive function, memory recall, processing speed, and neuroplasticity. Achieving this state requires proactively addressing the underlying molecular drivers of brain aging, such as telomere shortening and mitochondrial dysfunction. It is the clinical goal of interventions targeting neuroendocrine health and brain longevity.