What is the Origin of Non-Invasive VNS?

The concept is a technological evolution of traditional Vagus Nerve Stimulation, which was historically an invasive, surgically implanted device. The 'Non-Invasive' descriptor highlights the use of transcutaneous electrical stimulation. The vagus nerve, from the Latin vagus (wandering), is the tenth cranial nerve and the main component of the parasympathetic nervous system.

What is the Mechanism of Non-Invasive VNS?

The electrical stimulation travels afferently along the vagus nerve fibers to the nucleus tractus solitarius (NTS) in the brainstem, which then projects to areas involved in mood, stress, and inflammation. By increasing vagal tone, VNS enhances the body's capacity for relaxation and recovery, directly influencing the HPA axis by reducing the chronic secretion of stress hormones. This modulation also contributes to a reduction in systemic inflammation by inhibiting pro-inflammatory cytokine production through the cholinergic anti-inflammatory pathway.

Non-Invasive VNS ∞ Area

Non-Invasive VNS

Meaning

Non-Invasive Vagus Nerve Stimulation (VNS) is a therapeutic technique that uses electrical impulses delivered externally, typically to the neck or ear, to modulate the activity of the vagus nerve without requiring surgical implantation. This intervention is designed to influence the autonomic nervous system balance, promoting parasympathetic tone and reducing sympathetic overdrive. Clinically, it is utilized to address conditions related to chronic stress, inflammation, and mood regulation by leveraging the vagus nerve’s extensive connections to the brain and visceral organs.