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Non-Coding RNA Regulation

Meaning

The sophisticated biological control system exerted by RNA molecules that do not translate into proteins, such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), which fine-tune gene expression. These non-coding RNAs act as crucial molecular intermediaries, influencing the stability and translation of messenger RNA (mRNA) and altering chromatin structure. Their precise regulation is increasingly recognized as a vital mechanism in cellular aging, hormonal signaling, and disease pathology. This represents a complex, yet accessible, layer of genetic control.