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Nocturnal Testosterone Secretion

Meaning

Nocturnal Testosterone Secretion refers to the characteristic pulsatile release of testosterone, primarily from the Leydig cells, occurring during the deeper stages of non-REM sleep in males. This nighttime surge is physiologically significant as it often represents the highest concentration of circulating testosterone within a 24-hour period. Understanding this rhythm is essential because it drives much of the anabolic repair and recovery processes that occur during rest. A blunted nocturnal peak is a sensitive indicator of endocrine disruption.