Nocturnal Light Disruption is the detrimental physiological consequence of exposure to artificial light during the body’s biological night, defined as the period when the pineal gland is actively secreting melatonin. This exposure inappropriately signals biological daytime to the master clock, leading to a cascade of hormonal and metabolic dysregulation. It is a recognized environmental stressor impacting metabolic and mental health, including impaired glucose tolerance.
Origin
The term is a direct clinical descriptor of a common environmental challenge in modern society, rooted in the science of circadian biology and the non-visual effects of light. It emphasizes the profound disruptive effect of misplaced light signals on endogenous biological timing. The pervasive nature of modern lighting makes this a key clinical consideration.
Mechanism
Exposure to light, particularly in the blue spectrum, during the hours of darkness inhibits the release of melatonin, a key chronobiotic hormone, through the retinohypothalamic tract. This suppression acutely shifts the phase of the central circadian pacemaker in the suprachiasmatic nucleus (SCN), leading to internal desynchrony between the master clock and peripheral organ clocks, which impairs glucose tolerance and alters hormone secretion patterns.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.