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Nocturnal Hormone Pulsatility

Meaning

Nocturnal Hormone Pulsatility refers to the distinct, intermittent, and rhythmic bursts of hormone secretion that occur primarily during the sleep phase, a critical characteristic of endocrine signaling for numerous vital hormones. This pulsatile pattern, rather than a continuous release, is essential for maintaining target tissue receptor sensitivity and preventing desensitization. Key examples include the robust, high-amplitude pulses of Growth Hormone and the tightly regulated, cyclical release of Gonadotropin-Releasing Hormone (GnRH) that drives reproductive axis function.