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Nitric Oxide Bioavailability

Meaning

Nitric Oxide Bioavailability refers to the concentration of the gaseous signaling molecule nitric oxide (NO) that is readily available to exert its biological effects within the vascular endothelium and adjacent smooth muscle tissues. Optimal bioavailability is absolutely crucial for promoting balanced vasodilation, maintaining healthy, flexible blood flow, and inhibiting the pathological aggregation of platelets, thereby supporting superior cardiovascular function. A measurable reduction in NO bioavailability is a recognized early hallmark of endothelial dysfunction and a precursor to widespread vascular disease.