An advanced, forward-looking paradigm in longevity medicine that strategically moves beyond traditional symptom management to employ sophisticated biotechnologies and precision diagnostics aimed at targeting the fundamental, root causes of biological aging. This comprehensive approach integrates advanced tools like genomics, cellular therapies, and complex metabolic modulators for the express purpose of radical healthspan extension and age reversal. It represents the frontier of human health optimization.
Origin
This term reflects the current, rapid evolution of anti-aging research, transitioning from broad-spectrum interventions to highly targeted, molecular-level strategies enabled by breakthroughs in gene sequencing and cellular reprogramming. It signals the transition of the field from speculative concepts to one grounded in quantifiable biological engineering and clinical translation.
Mechanism
The mechanism centers on utilizing interventions that directly address the established hallmarks of aging, such as employing senolytics to selectively clear senescent cells and using NAD+ precursors to enhance mitochondrial bioenergetics. This multi-pronged strategy seeks to reverse or significantly slow the pace of biological decline by actively repairing accumulated cellular damage and resetting suboptimal cellular clock mechanisms.
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