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Neurotrophic Factor Signaling

Meaning

Neurotrophic Factor Signaling describes the complex cellular communication pathways mediated by neurotrophic factors, which are small proteins that support the survival, development, and function of neurons. These signaling molecules are essential for maintaining the structural integrity and plasticity of the nervous system throughout life. Optimal signaling is critical for processes like long-term potentiation, memory consolidation, and protecting neurons from excitotoxicity and oxidative stress. Disruption of this signaling cascade is implicated in various neurodegenerative and psychiatric conditions.