Neurotrophic Factor Modulation

Meaning

Neurotrophic Factor Modulation is a therapeutic strategy focused on influencing the synthesis, release, and receptor binding of neurotrophic factors, which are small proteins that support the survival, development, and function of neurons. The most clinically relevant factor is Brain-Derived Neurotrophic Factor (BDNF), which plays a critical role in neuroplasticity, cognitive health, and the central regulation of metabolism. In hormonal health, this modulation is crucial because many hormones, such as estrogen and testosterone, directly influence the expression of these factors. The goal is to enhance neuronal resilience and improve the structural integrity of the central nervous system.

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