The clinical strategies focused on ensuring adequate synthesis, recycling, and receptor function for key neurochemicals like serotonin, dopamine, GABA, and acetylcholine, which significantly modulate endocrine output. These systems serve as critical interfaces between the CNS and the pituitary/hypothalamus. Proper function here dictates upstream hormonal command signals.
Origin
This term reflects the integration of neuroscience with endocrinology, acknowledging that mood, stress perception, and sleep quality—all CNS functions—directly impact hormone axes. Support focuses on providing necessary precursors and co-factors.
Mechanism
Support operates by supplying the required amino acid precursors (e.g., L-tyrosine, 5-HTP) and enzymatic co-factors (e.g., B6, magnesium) for neurotransmitter synthesis. Furthermore, addressing receptor downregulation through lifestyle modification ensures that the hormonal signals being sent are appropriately received and translated into physiological action within the CNS. This system governs the rhythmicity of the HPA axis.
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