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Neurotransmitter Resource Depletion

Meaning

Neurotransmitter resource depletion refers to a clinical state where the reserves of key neurotransmitters, the chemical messengers that transmit signals across synapses, become chronically diminished, leading to impaired communication within the nervous system. This depletion is typically the result of prolonged, excessive demand—often due to chronic stress or nutrient deficiencies—that outpaces the body’s capacity for synthesis and reuptake. Clinically, this manifests as symptoms like chronic fatigue, mood instability, impaired focus, and reduced stress tolerance. Restoring these depleted resources is essential for neurological and psychological well-being.