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Neurotransmitter Regulation during Sleep

Meaning

Neurotransmitter regulation during sleep describes the dynamic and highly coordinated changes in the release and activity of key neurotransmitters, such as acetylcholine, serotonin, norepinephrine, and GABA, across different sleep stages. This regulation is fundamental to transitioning between wakefulness, non-REM sleep, and REM sleep, and it critically influences the restorative functions of the sleep state. Imbalances in this system can contribute to insomnia, excessive daytime sleepiness, and mood disorders.