Neurotransmitter Receptor Sensitivity

Meaning

Neurotransmitter receptor sensitivity refers to the responsiveness of postsynaptic neuronal receptors to the binding of specific neurotransmitters, which dictates the magnitude of the resulting cellular signal and subsequent physiological effect. This sensitivity is a dynamic and adaptable biological parameter, not merely a fixed quantity, and is subject to up-regulation or down-regulation in response to chronic exposure levels of the signaling molecule or changes in the surrounding hormonal milieu. Optimal receptor sensitivity is crucial for maintaining stable mood, cognitive function, and appropriate signaling between the central nervous system and the peripheral endocrine system.

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HRTioOctober 3, 2025

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