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Neurotransmitter Receptor Clustering

Meaning

Neurotransmitter receptor clustering is the highly regulated process by which specific receptors for neurotransmitters, such as glutamate or GABA, are rapidly aggregated and anchored at specialized sites on the postsynaptic membrane, forming functional synaptic connections. This spatial organization is essential for efficient synaptic transmission, allowing the neuron to respond effectively to chemical signals from the presynaptic terminal. The stability and density of these clusters are a direct reflection of synaptic strength and plasticity.