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Neurotransmitter-Endocrine Cross-Talk

Meaning

Neurotransmitter-endocrine cross-talk describes the complex, bidirectional communication and regulatory feedback loops between the nervous system’s chemical messengers (neurotransmitters) and the endocrine system’s hormones. This intricate signaling network ensures the coordinated control of vital physiological functions, including stress response, mood, metabolism, and reproduction. Disruptions in this cross-talk can lead to systemic dysregulation, manifesting as hormonal imbalances or neuropsychiatric symptoms.