Structured interventions aimed at achieving optimal concentrations and ratios of key neurotransmitters—such as serotonin, dopamine, GABA, and glutamate—within the central and peripheral nervous systems. Balance is necessary for stable mood, efficient cognition, and appropriate autonomic regulation. These protocols move beyond simple supplementation to address synthesis and degradation pathways.
Origin
Rooted in clinical neuropsychiatry and biochemistry, this concept recognizes that subjective well-being and function are dictated by the precise balance of chemical messengers in the synaptic cleft. Protocols are developed based on clinical assessment of functional deficits related to specific neurotransmitter imbalances.
Mechanism
The mechanism involves providing the necessary biochemical precursors, cofactors, and enzymes required for efficient neurotransmitter synthesis, such as L-tyrosine for catecholamines or 5-HTP for serotonin. Furthermore, protocols may aim to modulate reuptake transporters or receptor sensitivity to optimize signal duration and intensity. Achieving balance requires careful consideration of inhibitory versus excitatory signals for overall CNS stability.
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