Skip to main content

Neurosteroids and Cognition

Meaning

Neurosteroids and Cognition describes the profound influence of steroids synthesized de novo within the central and peripheral nervous systems on brain function, particularly memory, mood, and executive processes. These specialized steroids, such as allopregnanolone and DHEA, act rapidly as potent modulators of neurotransmitter receptors, distinct from the slower, genomic effects of circulating gonadal and adrenal hormones. The balance of neurosteroids is critical for neuroplasticity, stress resilience, and maintaining optimal cognitive health throughout the lifespan. Clinical interventions often seek to optimize neurosteroid levels to support neurological and emotional well-being.