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Neurosteroidogenic Modulation

Meaning

Neurosteroidogenic Modulation is the process of regulating the local synthesis and metabolism of neurosteroids, such as allopregnanolone and DHEA, directly within the central and peripheral nervous systems, independent of classical endocrine glands. This local production rapidly alters neuronal excitability, neurotransmitter receptor function, and synaptic plasticity, profoundly impacting mood, stress response, and cognitive processing. This mechanism provides a fast-acting, localized hormonal control over brain function.