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Neurosteroid Sensitivity

Meaning

Neurosteroid sensitivity describes the degree to which neurons and glial cells in the central and peripheral nervous systems respond to the presence and concentration of neurosteroids. These compounds are steroid molecules synthesized de novo in the nervous system, independent of peripheral endocrine glands, or derived from peripheral precursors. Altered sensitivity can significantly impact mood, cognition, stress response, and sleep architecture, presenting a therapeutic target in neurological and psychiatric conditions.