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Neurosteroid Production

Meaning

Neurosteroid production refers to the de novo synthesis of steroid hormones within the nervous system, specifically in glial cells and neurons, independent of classical steroidogenic glands. These steroids are not merely transported from peripheral sources; they are synthesized locally from cholesterol or steroid precursors, acting as neuromodulators and neuroregulators. Their localized synthesis allows for rapid, precise effects on neuronal excitability and synaptic function.