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NeuroSERM

Meaning

NeuroSERM is a portmanteau for Neuro-Selective Estrogen Receptor Modulator, representing a class of compounds designed to selectively modulate estrogen receptor activity specifically within the central nervous system, particularly the brain. Unlike traditional SERMs that target multiple tissues, a NeuroSERM aims to confer the beneficial neuroprotective, mood-regulating, and cognitive-enhancing effects of estrogen while minimizing peripheral side effects on tissues like the breast or uterus. This targeted action is a key development in managing neuroendocrine symptoms associated with hormonal fluctuations, such as those experienced during menopause or andropause.