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Neuroprotective Hormone Signaling

Meaning

Neuroprotective Hormone Signaling describes the beneficial, cell-level communication exerted by specific endogenous hormones that actively shield neurons from damage, promote synaptic plasticity, and support the maintenance of overall brain structure and function. Steroid hormones, such as estradiol, progesterone, and testosterone, are key players, exerting effects that mitigate oxidative stress, reduce inflammation, and stimulate neurogenesis. This signaling is essential for long-term cognitive health and resilience against neurodegenerative processes.