Specific, sustained dietary habits and combinations of foods that are clinically demonstrated to actively defend the central nervous system against age-related degeneration, oxidative stress, and chronic inflammation. These patterns are rich in antioxidants, anti-inflammatory compounds, and essential micronutrients that support mitochondrial health and synaptic plasticity. They are the nutritional foundation for long-term brain health and cognitive reserve.
Origin
This term is an evolution of general healthy eating guidelines, such as the Mediterranean Diet, formalized by the development of patterns like the MIND diet, which specifically integrate neuroscientific evidence. The concept is rooted in epidemiological studies that correlate long-term dietary intake with reduced incidence of cognitive decline and neurodegenerative diseases. It shifts the focus from single nutrients to the synergistic effect of whole food matrixes.
Mechanism
Neuroprotective Food Patterns function by reducing systemic and neuroinflammation through the provision of high-quality lipids and polyphenols that modulate the eicosanoid and cytokine cascades. They support the synthesis of neurotrophic factors, such as Brain-Derived Neurotrophic Factor (BDNF), which promotes the growth and survival of neurons and synapses. Furthermore, these patterns optimize gut microbiota health, which in turn influences the production of neuroactive metabolites that cross the blood-brain barrier.
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