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Neuroprotective Effects of Estrogen

Meaning

The Neuroprotective Effects of Estrogen describe the beneficial, non-reproductive actions of the steroid hormone 17β-estradiol and its specific metabolites in actively safeguarding neurons from oxidative damage, mitigating inflammation, and promoting essential synaptic plasticity within the central nervous system. This is a clinically significant area of study, particularly concerning the maintenance of brain health and cognitive function in women during the perimenopausal and post-menopausal transition. Estrogen’s influence is extensive, reaching far beyond reproductive tissues to include fundamental neural resilience.