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Neuronal Scaffolding

Meaning

Neuronal Scaffolding refers to the complex structural and molecular framework within the central nervous system, which is primarily composed of the neuronal cytoskeleton and the surrounding extracellular matrix, that provides essential mechanical support, facilitates efficient axonal transport, and precisely organizes synaptic connectivity. Maintaining the dynamic integrity and optimal stability of this internal scaffolding is absolutely paramount for long-term neurological health and the sustained, high-speed efficiency of all cognitive function. Damage or disruption to this critical structure is a molecular hallmark of various neurodegenerative processes.