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Neuronal Homeostasis

Meaning

Neuronal homeostasis describes the active, tightly regulated process by which individual neurons and the overall neural network maintain a stable internal environment necessary for optimal signaling and function. This delicate balance encompasses the precise regulation of ion concentrations, neurotransmitter levels, energy supply, and structural integrity within the brain. Hormonal health is inextricably linked to this state, as steroid hormones and neuropeptides directly modulate ion channel activity and synaptic plasticity. Disruption of neuronal homeostasis is a central feature in neuroendocrine disorders and cognitive decline.