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Neuronal Androgen Receptor

Meaning

The Neuronal Androgen Receptor (nAR) is a specific type of intracellular protein found within various cells of the central and peripheral nervous systems that binds to androgens, such as testosterone and dihydrotestosterone. Activation of this receptor is crucial for mediating the neuroprotective, mood-regulating, and cognitive-enhancing effects of male and female sex hormones. The presence and function of nARs highlight the direct influence of androgens on brain health, demonstrating that hormonal balance is essential not only for reproductive function but also for optimal neurological longevity. Dysfunction in nAR signaling can contribute to neurodegenerative conditions.